GEO series
Genetic background and oncogenic driver determines the genomic evolution and transcriptomics of mammary tumor metastasis
GSE278182
Mus musculus
Expression profiling by high throughput sequencing
74 samples
2025/07/30
GPL24247
Summary
Total RNA was isolated from matched primary mammary tumors and lung metastases from MMTV-Myc, MMTV-Her2 and C3TAg mouse models on homozygous FVB backgrounds. Primary tumors and lung metastases were also isolated from MMTV-PyMT on (AKR/J x FVB/NJ0, (BALB/cJ x FVB/NJ) and (SEA/GnJ x FVB/NJ)F1 animals. RNA-sequencing was performed to examine the expression differences of the primary tumors and lung metastases.
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Paper (PMID 40813609) ↗
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