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Single-cell RNA sequencing identifies Endothelial derived HBEGF promoting Pancreatic Beta Cell Proliferation via EGFR-Kmt5a-H4K20me Pathway [scRNA-seq]

GSE278860 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2024/12/10 Platform GPL34290
Summary
Pancreatic beta cells mass is dynamically regulated in response to increased physiological demands during pregnancy. We used single-cell RNA sequencing (scRNA-seq) to analyze the diversity and character of islets cells in pancreas.
Published in
Single-cell RNA sequencing identifies endothelial-derived HBEGF as promoting pancreatic beta cell proliferation in mice via the EGFR-Kmt5a-H4K20me pathway
Lai F, Zhou K, Ma Y et al. · Diabetologia 2025 · PMID 39694915 · doi:10.1007/s00125-024-06341-y
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Also filed as BioProject PRJNA1169192 and SRA study SRP536726. Searching any of these in the dataset finder brings you back here.

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