Identification of mRNAs as potential blood based biomarekrs for diagnosis and therapeutic monitoring of active tuberculosis
RNA-seq (gene expression) · human · 65 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 65 samples: 65 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE279063_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1170285 and SRA study SRP537330. Searching any of these in the dataset finder brings you back here.
Supports a case/control comparison: 36 samples read as cases, 14 as controls.
How we read this: Read from 65 sample titles: 65 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8560295 Blood, PD101m, patient at diagnossis
- GSM8560296 Blood, PD101m, patient during treatment
- GSM8560297 Blood, PD101m, patient after completion of treatment
- GSM8560298 Blood, PD107m, patient at diagnossis
- GSM8560299 Blood, PD107m, patient during treatment
- GSM8560300 Blood, PD107m, patient after completion of treatment
- GSM8560301 Blood, PD108m, patient at diagnossis
- GSM8560302 Blood, PD108m, patient during treatment
- GSM8560303 Blood, PD108m, patient after completion of treatment
- GSM8560304 Blood, PD111m, patient at diagnossis
- GSM8560305 Blood, PD111m, patient during treatment
- GSM8560306 Blood, PD111m, patient after completion of treatment
- GSM8560307 Blood, PD112m, patient at diagnossis
- GSM8560308 Blood, PD112m, patient during treatment
- GSM8560309 Blood, PD112m, patient after completion of treatment
- GSM8560310 Blood, PD116m, patient at diagnossis
- GSM8560311 Blood, PD116m, patient during treatment
- GSM8560312 Blood, PD116m, patient after completion of treatment
- GSM8560313 Blood, PD117m, patient at diagnossis
- GSM8560314 Blood, PD117m, patient during treatment
- GSM8560315 Blood, PD117m, patient after completion of treatment
- GSM8560316 Blood, PD118m, patient at diagnossis
- GSM8560317 Blood, PD118m, patient during treatment
- GSM8560318 Blood, PD118m, patient after completion of treatment
- GSM8560319 Blood, PD120m, patient at diagnossis
- GSM8560320 Blood, PD120m, patient during treatment
- GSM8560321 Blood, PD120m, patient after completion of treatment
- GSM8560322 Blood, PD127m, patient at diagnossis
- GSM8560323 Blood, PD127m, patient during treatment
- GSM8560324 Blood, PD127m, patient after completion of treatment
- GSM8560325 Blood, PD129m, patient at diagnossis
- GSM8560326 Blood, PD129m, patient during treatment
- GSM8560327 Blood, PD129m, patient after completion of treatment
- GSM8560328 Blood, PD137m, patient at diagnossis
- GSM8560329 Blood, PD137m, patient during treatment
- GSM8560330 Blood, PD137m, patient after completion of treatment
- GSM8560331 Blood, PD231m, latent tuberculosis infection
- GSM8560332 Blood, PD236m, latent tuberculosis infection
- GSM8560333 Blood, PD237m, latent tuberculosis infection
- GSM8560334 Blood, PD244m, latent tuberculosis infection
+ 25 more — browse all 65 samples with per-sample file links →
- GSE287043 Unique Mycobacterium tuberculosis-specific blood immune signatures in sarcoidosis: implications for clinical diagnosis 542 samples shares tuberculosis, diagnosis
- GSE268177 Modulating alternative splicing of MECP2: A potential therapeutic strategy for Rett syndrome 93 samples shares therapeutic, potential
- GSE273036 Multi-Omics Analysis and Molecular Subtypes Provide Potential Therapeutic Implications in Fumarate Hydratase-deficient Renal Cell Carcinoma 93 samples shares therapeutic, potential
- GSE335924 RNA-seq Identifies FOS as a Potential Therapeutic Target Activating Neural Stem Cells via miR-21/SOX2 Pathway in Hypertensive Intracerebral Hemorrhage 53 samples shares therapeutic, potential
- GSE145057 Establishment of a human tongue cancer organoid biobank enables early diagnosis, prognosis, and identification of therapeutic targets 25 samples shares therapeutic, diagnosis
- GSE245935 Chemo-senolytic therapeutic potential against angiosarcoma 13 samples shares therapeutic, potential
- GSE217531 Exploring the potential mechanism of artesunate in intervening with glioma cells with distinct therapeutic effects on the basis of transcriptome sequencing and network pharmacology 12 samples shares therapeutic, potential
- GSE317656 Erastin-Induced Ferroptosis Enhances Natural Killer Cell Anti-Tumor Activity and Offers Therapeutic Potential in Neuroblastoma 12 samples shares therapeutic, potential
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.