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Transcriptomic profiling of MDA-MB-453 breast cancer cells following ZNF207 overexpression

GSE279294 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2024/10/16 Platform GPL24676
Summary
This RNA-sequencing study was designed to characterize transcriptional changes associated with ZNF207 overexpression in MDA-MB-453 breast cancer cells and to identify downstream pathways. MDA-MB-453 cells transfected with a control vector or a ZNF207-overexpression construct were analyzed, with three independent biological replicates per group. Differential expression and pathway enrichment analyses were performed to compare ZNF207-overexpressing cells with control cells. The dataset itself does not contain drug-treated samples. Findings from separate functional assays in the associated manuscript indicate that ZNF207 is linked to breast cancer progression and chemotherapy response.
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Direct links to NCBI, no account and no request form: the whole study as GSE279294_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1171627 and SRA study SRP537889. Searching any of these in the dataset finder brings you back here.

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