G-quadruplex structures regulate long-range transcriptional reprogramming to promote drug resistance in ovarian cancer [ChIP-seq]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 12 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 12 samples: 3 × PEO1 A, Input, vs 3 × PEO1 A, G4 ChIP, vs 3 × PEO4 A, Input, vs 3 × PEO4 A, G4 ChIP,Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- G-quadruplex structures regulate long-range transcriptional reprogramming to promote drug resistance in ovarian cancer cellsGenome biology · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE279497_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1173145 and SRA study SRP538658. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8573456 PEO1 A, Input, Rep1 PEO1 A, Input,
- GSM8573457 PEO1 A, G4 ChIP, Rep1 PEO1 A, G4 ChIP,
- GSM8573458 PEO1 A, Input, Rep2 PEO1 A, Input,
- GSM8573459 PEO1 A, G4 ChIP, Rep2 PEO1 A, G4 ChIP,
- GSM8573460 PEO1 A, Input, Rep3 PEO1 A, Input,
- GSM8573461 PEO1 A, G4 ChIP, Rep3 PEO1 A, G4 ChIP,
- GSM8573462 PEO4 A, Input, Rep1 PEO4 A, Input,
- GSM8573463 PEO4 A, G4 ChIP, Rep1 PEO4 A, G4 ChIP,
- GSM8573464 PEO4 A, Input, Rep2 PEO4 A, Input,
- GSM8573465 PEO4 A, G4 ChIP, Rep2 PEO4 A, G4 ChIP,
- GSM8573466 PEO4 A, Input, Rep3 PEO4 A, Input,
- GSM8573467 PEO4 A, G4 ChIP, Rep3 PEO4 A, G4 ChIP,
- GSE279641 G-quadruplex structures regulate long-range transcriptional reprogramming to promote drug resistance in ovarian cancer [CUT&Tag] 12 samples shares reprogramming, g-quadruplex, structures, long-range, resistance, regulate, promote
- GSE308983 Reprogramming lineage features promotes epithelial behavior in carcinoma cells [ChIP-Seq] 23 samples shares reprogramming, chip-seq, promote
- GSE239270 Investigate FOXA2, NKX2-1, CTCF and P300 cistrome and enhancer (H3K27ac and H3k4me1) reprogramming during NEPC transformation by ChIP-seq. 104 samples shares reprogramming, chip-seq
- GSE307329 Continuous NRTI-based antiretroviral therapy induces progressive senescence-like reprogramming of alveolar macrophages [ChIP-seq] 74 samples shares reprogramming, chip-seq
- GSE206726 Epigenetic reprogramming of the mesenchymal state by SUV39H1/H2 [ChIP-Seq] 42 samples shares reprogramming, chip-seq
- GSE311971 Regulation of lineage reprogramming by dynamic chromatin SUMOylation (ChIP-seq) 41 samples shares reprogramming, chip-seq
- GSE261321 NF-κB- and TET2-mediated macrophage reprogramming overrides the anti-inflammatory effects of hypoxia and improves responses in human cancer ChIP-Seq). 24 samples shares reprogramming, chip-seq
- GSE97680 Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance [ATAC-seq] 17 samples shares reprogramming, resistance
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.