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Extracellular Vesicles Derived from Inflammatory Cardiomyocytes Mediate Macrophage Polarization and Alleviate Myocarditis via p38 MAPK Pathway

GSE279575 Mus musculus Expression profiling by high throughput sequencing 8 samples Submitted 2024/10/23 Platform GPL24247
Summary
EVs derived from lipopolysaccharide (LPS)-stimulated cardiomyocytes (EVLPS) exhibit anti-inflammatory effects on macrophages and reduce cardiac inflammation in mice.To investigate gene expression changes induced by EVLPS treatment in inflammatory RAW264.7 using next-generation sequencing,we performed RNAseq.
Published in
Large extracellular vesicles derived from LPS-preconditioned cardiomyocytes alleviate myocarditis via mediating macrophage polarization and modulating p38 MAPK pathway
Jiang Y, You Y, Xie Y et al. · Frontiers in immunology 2025 · PMID 40995365 · doi:10.3389/fimmu.2025.1629676
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Also filed as BioProject PRJNA1173537 and SRA study SRP538911. Searching any of these in the dataset finder brings you back here.

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