← BioTransfer GEO Dataset Finder
GEO series

Transcriptome analysis of the course of ischemic stroke from acute to chronic phase in mice

GSE279665 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2026/02/20 Platform GPL30172
Summary
We examined comprehensive gene expression in the mouse brain under physiological conditions at single cell-transcriptomic levels. In addition, Sytox-negative cells were sorted and analyzed for gene expression. We performed single cell RNA-seq for mouse brain and found that the neurons could no recovered for further analyses. We successfully obtained oligodendrocyte progenitor cells (OPCs), oligodendrocytes, microglia, endothelial cells, and pericytes, but were unable to obtain neurons. Additionally, we were only able to obtain astrocytes to a limited extent.We were able to examine comprehensive gene expression in the physiological brain.
Published in
Characterizing stroke-related cellular changes in the surviving neurons of mouse ischemic stroke
Ikegami T, Sasaki T, Shimbo T et al. · Neurochemistry international 2025 · PMID 41223896 · doi:10.1016/j.neuint.2025.106086
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE279665_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1174055 and SRA study SRP539082. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 6 more — browse all 6 samples with per-sample file links →

Similar datasets

Search all mouse RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.