Gene expression changes in skin of dihydrotestosterone-induced mice after treatment of a newly-developed traditional Chinese medicine formula, Hanlianxiang.
RNA-seq (gene expression) · mouse · 24 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 24 samples: 6 conditions, mostly with about 4 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE279813_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1174732 and SRA study SRP539365. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 24 samples.
How we read this: 6 replicated groups read from 24 sample titles; they account for 24 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8581462 control_day_10_1 control_day_10
- GSM8581463 control_day_10_2 control_day_10
- GSM8581464 control_day_10_3 control_day_10
- GSM8581465 control_day_10_4 control_day_10
- GSM8581466 model_day_10_1 model_day_10
- GSM8581467 model_day_10_2 model_day_10
- GSM8581468 model_day_10_3 model_day_10
- GSM8581469 model_day_10_4 model_day_10
- GSM8581470 treat_day_10_1 treat_day_10
- GSM8581471 treat_day_10_2 treat_day_10
- GSM8581472 treat_day_10_3 treat_day_10
- GSM8581473 treat_day_10_4 treat_day_10
- GSM8581474 control_day_15_1 control_day_15
- GSM8581475 control_day_15_2 control_day_15
- GSM8581476 control_day_15_3 control_day_15
- GSM8581477 control_day_15_4 control_day_15
- GSM8581478 model_day_15_1 model_day_15
- GSM8581479 model_day_15_2 model_day_15
- GSM8581480 model_day_15_3 model_day_15
- GSM8581481 model_day_15_4 model_day_15
- GSM8581482 treat_day_15_1 treat_day_15
- GSM8581483 treat_day_15_2 treat_day_15
- GSM8581484 treat_day_15_3 treat_day_15
- GSM8581485 treat_day_15_4 treat_day_15
- GSE253869 A traditional Chinese medicine decoction developed based on the theory of “Yang transforming into Qi with Yin constituting Form” suppresses hepatic tumorigenesis in mouse models 16 samples shares traditional, medicine, chinese
- GSE269502 Traditional Chinese Medicine JianPiHuaTan Formula Improving Quality of Life and Survival in Patients with Colorectal Cancer through RAS/RAF Downstream Signaling Pathways 6 samples shares traditional, medicine, chinese
- GSE276409 The antitumor function of Th17-derived Th1 cell is better than traditional Th1 and Th17 cells 9 samples shares traditional
- GSE308738 Integrated Multi-omics Profiling of Mouse Brain Tissue Using the AllPrep Methods versus Traditional Extraction Methods 6 samples shares traditional
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.