GEO series
Reprogramming of epidermal keratinocytes by PITX1 transforms the cutaneous cellular landscape and promotes wound healing [scRNA-seq]
GSE280067
Mus musculus
Expression profiling by high throughput sequencing
36 samples
2024/11/22
GPL24247
Summary
Skin injuries heal slowly, compared to oral epithelial tissues, and often do not regenerate lost adnexa. Using a murine mouse model expressing the oral epithelial transcription factor PITX1 in the skin, we performed scRNA-seq in healthy and wounded skin and healthy oral mucosa to delineate the cellular and molecular changes underpinning the superior oral wounding response.
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Paper (PMID 39480496) ↗
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