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Effects of moderate intensity exercise on liver metabolism in mice based on multi-omics analysis

GSE280324 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2025/01/02 Platform GPL23479
Summary
Physical exercise is beneficial to keep physical and mental health. The molecular mechanisms underlying exercise are still worth exploring.The healthy adult mice after six weeks of moderate-intensity exercise (experimental group) and sedentary mice (control group) were used to perform transcriptomic, proteomic, lactylation modification, and metabolomics analysis. In addition, gene sets related to hypoxia, glycolysis, and fatty acid metabolism were used to aid in the screening of hub genes. The mMCP-counter was employed to evaluate infiltration of immune cells in murine liver tissues.
Published in
Effects of moderate intensity exercise on liver metabolism in mice based on multi-omics analysis
Wang F, Wu W, He X et al. · Scientific reports 2024 · PMID 39730655 · doi:10.1038/s41598-024-82150-y
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Also filed as BioProject PRJNA1177849 and SRA study SRP540860. Searching any of these in the dataset finder brings you back here.

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