← BioTransfer GEO Dataset Finder
GEO series

liver transcriptional changes with rs6190 SNP genotype (R24K in GR protein)

GSE280494 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2024/12/19 Platform GPL24247
Summary
this dataset encompasses the transcriptomic changes elicited in liver tissues of 4-months-old mice with either the artificially-knock-in rs6190 genotype, or the control non-mutant (WT) genotype.
Published in
The human glucocorticoid receptor variant rs6190 increases blood cholesterol and promotes atherosclerosis
Durumutla HB, Haller A, Noble G et al. · bioRxiv : the preprint server for biology 2025 · PMID 39677678 · doi:10.1101/2024.11.27.625727
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE280494_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1178700 and SRA study SRP541632. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 6 more — browse all 6 samples with per-sample file links →

Similar datasets

Search all mouse RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.