GEO series
scRNA of lichen planus
GSE280584
Homo sapiens
Expression profiling by high throughput sequencing
41 samples
2024/12/14
GPL24676
Summary
An early and sustained clinical response was seen, with 83.3% of patients responsive at week 16. Our molecular data identified a unique, oligoclonal IFN-γ, CD8+, CXCL13+ cytotoxic T-cell population in LP skin and demonstrated a rapid decrease in IFN signature within 2 weeks of treatment, most prominently in the basal layer of the epidermis.
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