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Spatially-restricted and ontogenically-distinct hepatic macrophages are required for tissue repair.

GSE280652 Mus musculus Expression profiling by high throughput sequencing; Other 42 samples 2024/10/30 GPL24247GPL21103
Summary
Analysis of single cell RNA-seq, CITE-seq data and bulk RNA-seq data on cells isolated from the livers of mice following PBS and APAP (paracetamol/acetaminophen) administration. Spatial Transcriptomics analysis was performed using 10x Visium platform on mouse livers 48hrs post PBS or APAP administration. We also analysed single cell RNA-seq data on CD64+F4/80+ macrophages isolated from the livers of Trem2 fl/fl mice and CD64CRE Trem2 fl/fl mice.
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