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Phosphorylation of Runx protein controls thymocyte fate.

GSE280658 Mus musculus Genome binding/occupancy profiling by high throughput sequencing 8 samples Submitted 2026/02/19 Platform GPL17021
Summary
To understand the impact of Runx3 WRPW variant on the histone marks, we performed ChIP-seq of H3K4me3 and H3K27me3 using Runx3 +/+ and Runx3 +/WRPW mature CD8 SP thymocytes.
Published in
Phosphorylation of Runx protein controls helper CD4(+) T cell versus cytotoxic CD8(+) T cell lineage choice
Ogawa C, Okuyama K, Kojo S et al. · Nature immunology 2026 · PMID 41714737 · doi:10.1038/s41590-026-02441-6
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Also filed as BioProject PRJNA1179904 and SRA study SRP542149. Searching any of these in the dataset finder brings you back here.

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