The RNA binding protein LIN28A mediates chromatin dynamics during neuronal differentiation
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 24 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 24 samples: 24 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- The RNA binding protein LIN28A mediates chromatin dynamics during neuronal differentiationCell death and differentiation · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE306869_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1312830 and SRA study SRP614748. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 24 sample titles: 24 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9211078 H3K27ME3 KO ESC 1 (Chip)
- GSM9211079 H3K27ME3 KO ESC 1 (IP)
- GSM9211080 H3K27ME3 KO ESC 2 (Chip)
- GSM9211081 H3K27ME3 KO ESC 2 (IP)
- GSM9211082 H3K27ME3 KO ESC 3 (Chip)
- GSM9211083 H3K27ME3 KO ESC 3 (IP)
- GSM9211084 H3K27ME3 WT ESC 1 (Chip)
- GSM9211085 H3K27ME3 WT ESC 1 (Input)
- GSM9211086 H3K27ME3 WT ESC2 (Chip)
- GSM9211087 H3K27ME3 WT ESC 2 (Input)
- GSM9211088 H3K27ME3 WT ESC 3 (Chip)
- GSM9211089 H3K27ME3 WT ESC 3 (Input)
- GSM9211090 H3K27ME3 KO sFEB 1(Chip)
- GSM9211091 H3K27ME3 KO sFEB 1 (Input)
- GSM9211092 H3K27ME3 KO sFEB 2 (Chip)
- GSM9211093 H3K27ME3 KO sFEB 2 (Input)
- GSM9211094 H3K27ME3 KO sFEB 3 (Chip)
- GSM9211095 H3K27ME3 KO sFEB 3 (Input)
- GSM9211096 H3K27ME3 WT sFEB 1 (Chip)
- GSM9211097 H3K27ME3 WT sFEB 1 (Input)
- GSM9211098 H3K27ME3 WT sFEB 2 (Chip)
- GSM9211099 H3K27ME3 WT sFEB 2 (Input)
- GSM9211100 H3K27ME3 WT sFEB 3 (Chip)
- GSM9211101 H3K27ME3 WT sFEB 3 (Input)
- GSE310322 Mapping self-associating chromatin hubs identifies Id proteins as key determinants of exhausted T cell fate 37 samples shares chromatin, protein
- GSE72539 CTCF binding polarity determines chromatin looping [4C] 504 samples shares chromatin, binding
- GSE264193 H3K27 dimethylation dynamics reveal stepwise establishment of facultative heterochromatin in early mouse embryos [ChIP-seq] 57 samples shares chromatin, dynamics
- GSE249978 Egr1 is a sex-specific regulator of neuronal chromatin, synaptic plasticity, and behaviour 52 samples shares chromatin, neuronal
- GSE263333 Spatial-Mux-seq: Multiplexed spatial mapping of chromatin features, transcriptome, and proteins at tissue scale 12 samples shares chromatin, protein
- GSE272524 Chromatin-dependent motif syntax defines differentiation trajectories [ChIP-seq] 76 samples shares chromatin
- GSE169555 Embryonic lumenogenesis is controlled by selective mRNA decay triggered by LIN28A relocation 146 samples shares lin28a
- GSE262720 Gene expression data of Lin28a-positive MuSCs using RNA-seq and RIP-seq 14 samples shares lin28a
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.