GEO series
The role of RUNX2 and BHLHE40 in pathologically relevant CD4-positive tissue-resident T-cells in Crohn's disease. (scMultiome)
GSE280714
Homo sapiens
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
12 samples
2025/08/14
GPL24676
Summary
Tissue-resident T-cells (TRM) are deeply involved in immune memory at the site of inflammation. Here, we identified two key transcription factors, RUNX2 and BHLHE40 as regulators of pathologically relevant CD4-positive TRM in the inflamed gut mucosa of Crohn’s disease patients.
Download
NCBI GEO page ↗
Paper (PMID 40906156) ↗
{# Names what the click gives you. "Open in finder" meant nothing to a
visitor who arrived from a search engine and has never seen the tool. #}
Find more
human ChIP / ATAC / CUT&Tag datasets →
Similar datasets
- GSE323364 Coordinating catalytic and non-canonical functions of EZH2 sensitizes tumors to CAR-T cell therapy 42 samples
- GSE324208 Epigenetic reprogramming drives cellular and phenotypic plasticity in liposarcoma 42 samples
- GSE281743 Epigenetic Subtypes of High-Grade T1 Bladder Cancer Reveal Intra-Tumor Heterogeneity and Distinct Interactions with Tumor Microenvironment 41 samples
- GSE308361 Spatial biology reveals macrophage dysfunction in immunosuppressed non-melanoma skin cancer 16 samples
- GSE328578 CBFA2T3-GLIS2 fusion-mediated mSWI/SNF chromatin remodeler disruption generates cancer-specific dependencies in AMKL 156 samples
- GSE330130 A multi-omics characterization of the human lumbar spinal cord and motor cortex reveals non-overlapping molecular signatures in ALS [snRNA-Seq; snATAC-Seq] 87 samples
- GSE335210 SOX9-BAF multi-omics profiling in human colon cancer cell models 173 samples
- GSE307670 Epigenetic reprogramming of stromal cell states underpins pathologic tissue niches in Crohn’s disease 148 samples
Share this dataset
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.