Evolutionary fingerprint in rodent PD1 confers weakened activity and enhanced tumor immunity compared to human PD1

Direct links to NCBI, no account and no request form: the whole study as GSE280853_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 4 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1180928 and SRA study SRP542617. Searching any of these in the dataset finder brings you back here.

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• GSE270050 Expansion of Tumor-Infiltrating CD8+ T Cell Clonotypes Occurs in the Spleen in Response to Immune Checkpoint Blockade 29 samples
• GSE281706 Omental support of ovarian tumor cell growth is unabated in the absence of mature adipocytes 24 samples
• GSE317032 Non-cytolytic viral vaccine vectors induce durable effector-memory CD8 T cell immunity by triggering type I interferon 18 samples
• GSE276667 A multivalent mRNA vaccine elicits robust immune responses and confers protection in a murine model of monkeypox virus infection 18 samples
• GSE327213 Increased mRNA translation delays tumor initiation and exposes a therapeutic vulnerability in lung cancer 16 samples
• GSE215963 Subclonal evolution revealed by single-cell profiles of expressed mutations identifies adaptation mechanisms to immunotherapy in melanoma. 1497 samples
• GSE231596 GI-SINE Analyses 195 samples

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