Ongoing replication stress tolerance and clonal T cell responses distinguish liver and lung recurrence and outcomes in pancreatic cancer
RNA-seq (gene expression) · human · 794 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Topic
- Pancreatic cancerThis series is part of our curated briefing on it.
- Samples
- 794 samples: 352 distinct titles, 48 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Ongoing replication stress tolerance and clonal T cell responses distinguish liver and lung recurrence and outcomes in pancreatic cancerNature cancer · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE281129_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1182514. Searching any of these in the dataset finder brings you back here.
How we read this: Read from the first 400 of 794 sample titles: 352 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM6206002 ST-00007061-T
- GSM6206003 ST-00007067-T
- GSM6206004 ST-00007071-T
- GSM6206005 ST-00007085-T
- GSM6206006 ST-00007099-T
- GSM6206007 ST-00007120-T
- GSM6206008 ST-00006650-M
- GSM6206009 ST-00005813-T
- GSM6206010 ST-00007165-T
- GSM6206011 ST-00007146-T
- GSM6206012 ST-00005536-T
- GSM6206013 ST-00007168-T
- GSM6206014 ST-00007174-T
- GSM6206015 ST-00007178-T
- GSM6206016 ST-00007179-T
- GSM6206017 ST-00007180-T
- GSM6206018 ST-00007377-M
- GSM6206019 ST-00007183-T
- GSM6206020 ST-00007185-T
- GSM6206021 ST-00007402-M
- GSM6206022 ST-00007193-T
- GSM6206023 ST-00007195-T
- GSM6206024 ST-00007203-T
- GSM6206025 ST-00007206-T
- GSM6206026 ST-00007369-M
- GSM6206027 ST-00007208-T
- GSM6206028 ST-00007213-T
- GSM6206029 ST-00007216-T
- GSM6206030 ST-00007223-M
- GSM6206031 ST-00007175-T
- GSM6206032 ST-00006371-T
- GSM6206033 ST-00007381-M
- GSM6206034 ST-00007234-T
- GSM6206035 ST-00007239-T
- GSM6206036 ST-00007380-M
- GSM6206037 ST-00007255-T
- GSM6206038 ST-00007257-T
- GSM6206039 ST-00007256-T
- GSM6206040 ST-00007266-T
- GSM6206041 ST-00007267-T
+ 754 more — browse all 794 samples with per-sample file links →
- GSE143584 Gene expression from laser capture microdissected epithelium and stroma during pancreatic carcinogenesis 366 samples same disease briefing · shares pancreatic
- GSE71729 Virtual Microdissection of Pancreatic Ductal Adenocarcinoma Reveals Tumor and Stroma Subtypes. 357 samples same disease briefing · shares pancreatic
- GSE113616 Stromal Fibroblasts Drive Single Cell Heterogeneity in Pancreatic Cancer 189 samples same disease briefing · shares pancreatic
- GSE134236 Mutant Kras co-opts a progenitor-derived enhancer network to initiate pancreatic tumorigenesis 166 samples same disease briefing · shares pancreatic
- GSE81314 Shotgun sequencing of 5-hydroxymethylcysotine circulating cell-free DNA from the blood distinguishes solid tumor tissues of origin 126 samples same disease briefing · shares distinguish
- GSE11838 Pancreatic Tumor vs Various Tissue Normals 107 samples same disease briefing · shares pancreatic
- GSE102238 Gene expression signatures associated with Perineural Invasion in pancreatic ductal adenocarcinoma 100 samples same disease briefing · shares pancreatic
- GSE149103 Integrative Hi-C maps of pancreatic cancer 66 samples same disease briefing · shares pancreatic
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.