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CROP-seq of 20 MASLD-associated differential activity variants from HepG2 MPRA screen

GSE281160 Homo sapiens Expression profiling by high throughput sequencing 7 samples Submitted 2026/03/16 Platform GPL34284
Summary
We performed CROP-seq to 20 MASLD-associated differential activity variants from HepG2 MPRA screen. This provides a powerful strategy for accurately locating the target gene pool associated with functional variants.
Published in
Integrative analyses elucidate transcriptional regulatory functions of risk alleles for metabolic liver disease
Zhu B, He N, Xiao Y et al. · Nature genetics 2026 · PMID 42230773 · doi:10.1038/s41588-026-02617-8
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Also filed as BioProject PRJNA1182473 and SRA study SRP543370. Searching any of these in the dataset finder brings you back here.

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