GEO series
The Impact of PPARβ/ agonism/antagonism on human bone-marrow-derived Mesenchymal Stromal Cells
GSE281162
Homo sapiens
Expression profiling by high throughput sequencing
18 samples
2026/05/06
GPL24676
Summary
PPARβ/ -ligands are present in the acute respiratory syndrome (ARDS) lung in abundance. Mesenchymal Stromal Cells (MSCs) have shown poor results in ARDS-based clinical trials. In order to determine the potential impact of PPARβ/ agonism/antagonism on human bone-marrow-derived MSCs in vitro, we activated or inhibited the receptor on the cells and/or licensed them with 5ng/ml TNF⍺.
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Paper (PMID 42007763) ↗
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