← BioTransfer GEO Dataset Finder
GEO series

Destruction of VISTA by TRIM25 ablation in T cells potentiates cancer immunotherapy

GSE281314 Mus musculus Expression profiling by high throughput sequencing 4 samples Submitted 2025/09/15 Platform GPL24247
Summary
To gain deeper insights into the role of Trim25 expression in T cells in regulating tumor microenvironment dynamics, we performed single-cell RNA sequencing on purified CD45+ immune cells isolated from MC38 xenografts harvested from either Trim25 cKO or WT C57BL/6 mice.
Published in
Destruction of VISTA by TRIM25 ablation in T cells potentiates cancer immunotherapy
Sun Y, Zhang Z, Li H et al. · Cell research 2025 · PMID 41225152 · doi:10.1038/s41422-025-01186-5
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE281314_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 4 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1183363 and SRA study SRP543823. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 4 more — browse all 4 samples with per-sample file links →

Similar datasets

Search all mouse RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.