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GRHL2 derepression triggers pathophysiological hepatocyte to cholangiocyte transdifferentiation [RNAseq_HepG2_EZHi]

GSE281712 Homo sapiens Expression profiling by high throughput sequencing 8 samples Submitted 2025/12/30 Platform GPL28038
Summary
Transcriptome of human HepG2 cells treated or not with Ezh1/2 inhibitors (UNC1999 and Valmetostat Tosylate).
Published in
Derepression of the epithelial transcription factor GRHL2 promotes direct hepatocyte-to-cholangiocyte transdifferentiation
Vasseur L, Gheeraert C, Dubois-Chevalier J et al. · PLoS biology 2025 · PMID 41385584 · doi:10.1371/journal.pbio.3003547
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Also filed as BioProject PRJNA1185274 and SRA study SRP544754. Searching any of these in the dataset finder brings you back here.

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