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Nanostructured Lipid Carriers based mRNA vaccine leads to a T cell–inflamed tumor microenvironment favorable for improving PD-1/PD-L1 blocking therapy and long-term immunity in a cold tumor model

GSE282402 Mus musculus Expression profiling by high throughput sequencing 8 samples Submitted 2025/02/05 Platform GPL28457
Summary
Using RNA-seq analysis, we have described the impact of a mRNA based vaccine on intratumoral immune-related transcriptional signature in a B16-OVA cold model
Published in
Nanostructured lipid carriers based mRNA vaccine leads to a T cell-inflamed tumour microenvironment favourable for improving PD-1/PD-L1 blocking therapy and long-term immunity in a cold tumour model
Fournier C, Mercey-Ressejac M, Derangère V et al. · EBioMedicine 2025 · PMID 39793480 · doi:10.1016/j.ebiom.2024.105543
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Also filed as BioProject PRJNA1188504 and SRA study SRP546444. Searching any of these in the dataset finder brings you back here.

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