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Single-cell RNA sequencing of human LECs derived from human skin and subcutaneous adipose tissue [CITE-Seq]

GSE282416 Homo sapiens Expression profiling by high throughput sequencing; Other 6 samples Submitted 2025/09/15 Platform GPL24676
Summary
We performed single-cell RNA sequencing (10X) on human lymphatic endothelial cells (LECs) isolated from human skin and subcutaneous adipose tissue. The goal was to analyze the different sub-populations of LECs present in those tissues (e.g. capillary, pre-collector, collector), which would give new insights into the human biology of lymphatics vessels present in skin and adipose tissue.
Published in
Transcriptomics- and 3D imaging-based characterization of the lymphatic vasculature in human skin
Bauer A, Zambounis L, Kritikos I et al. · The Journal of experimental medicine 2026 · PMID 41186588 · doi:10.1084/jem.20242353
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Direct links to NCBI, no account and no request form: the whole study as GSE282416_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1188555 and SRA study SRP546471. Searching any of these in the dataset finder brings you back here.

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