Transcriptomic changes in paired eutopic and ectopic endometrium of ovarian endometriosis

The pathogenesis and mechanisms underlying endometriosis are still not fully understood. Emerging studies highlight that altered genes expressions may play a role in disease onset and progression. This research investigates critical genes gain further insight into the molecular basis of endometriosis. Through high-throughput sequencing, we performed paired expression analyses of mRNAs, microRNAs and lncRNAs in ectopic and paired eutopic endometrial tissues from five patients with ovarian endometriosis.Our findings shed new light on the regulatory networks involved, potentially guiding future strategies for replacement therapy in endometriosis.