Age and cell type specific specific effects of histone variant H2BE in the brain
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 47 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 47 samples: 15 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Age- and cell-type-specific effects of histone variant H2BE in the brainCell reports · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE282578_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1189161 and SRA study SRP546649. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 43 samples.
How we read this: 15 replicated groups read from 47 sample titles; they account for 43 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8644115 Male P0 bio rep 1 Male P0
- GSM8644116 Male P0 bio rep 2 Male P0
- GSM8644117 Male P0 bio rep 3 Male P0
- GSM8644118 Male P0 bio rep 4 Male P0
- GSM8644119 Male P14 bio rep 1 Male P14
- GSM8644120 Male P14 bio rep 2 Male P14
- GSM8644121 Male P14 bio rep 3 Male P14
- GSM8644122 Male P14 bio rep 4 Male P14
- GSM8644123 Male P28 bio rep 1 Male P28
- GSM8644124 Male P28 bio rep 2 Male P28
- GSM8644125 Male P28 bio rep 3 Male P28
- GSM8644126 Male P28 bio rep 4 Male P28
- GSM8644127 WT P1 bio rep 1 WT P1
- GSM8644128 WT P1 bio rep 2 WT P1
- GSM8644129 WT P1 bio rep 3 WT P1
- GSM8644130 WT P1 bio rep merged
- GSM8645472 H2BE bio rep 1 H2BE
- GSM8645473 H2BE bio rep 2 H2BE
- GSM8645474 H2BE bio rep 3 H2BE
- GSM8645475 IgG bio rep 1 IgG
- GSM8645476 IgG bio rep 2 IgG
- GSM8645477 IgG bio rep 3 IgG
- GSM8645478 Young male WT bio rep 1 Young male WT
- GSM8645479 Young male WT bio rep 2 Young male WT
- GSM8645480 Young male WT bio rep 3 Young male WT
- GSM8645481 Young male KO bio rep 1 Young male KO
- GSM8645482 Young male KO bio rep 2 Young male KO
- GSM8645483 Young male KO bio rep 3 Young male KO
- GSM8645484 Old male WT bio rep 1 Old male WT
- GSM8645485 Old male WT bio rep 2 Old male WT
- GSM8645486 Old male KO bio rep 1 Old male KO
- GSM8645487 Old male KO bio rep 2 Old male KO
- GSM9053672 3mo bio rep 1 3mo
- GSM9053673 3mo bio rep 2 3mo
- GSM9053674 12mo bio rep 1 12mo
- GSM9053675 12mo bio rep 2 12mo
- GSM9053676 18mo bio rep 1 18mo
- GSM9053677 18mo bio rep 2 18mo
- GSM9053678 Control bio rep 1 Control
- GSM9053679 Control bio rep 2 Control
+ 7 more — browse all 47 samples with per-sample file links →
- GSE291274 The placentalia specific histone H3.4 promotes germ cell development and reproductive fitness 167 samples shares specific, histone
- GSE254090 A cell type-aware framework for nominating non-coding variants in Mendelian regulatory disorders 87 samples shares variant, type
- GSE331488 A global view of cell-type-specific temporal dynamics in mammalian aging [I] 771 samples shares specific, type
- GSE331489 A global view of cell-type-specific temporal dynamics in mammalian aging [II] 725 samples shares specific, type
- GSE269748 A single-cell atlas deconstructs heterogeneity across multiple models in murine traumatic brain injury and identifies novel cell-specific targets 36 samples shares specific, brain
- GSE267938 Functional optic tract rewiring via subtype- and target-specific axonal regeneration and presynaptic activity enhancement 256 samples shares specific, type
- GSE306031 Single-Nucleus Transcriptomics Reveals Cell Type-Specific Remodeling and Epilepsy Associated Microglia 31 samples shares specific, type
- GSE283392 Distinct use of super-enhancer elements controls cell type-specific CD25 transcription and function 25 samples shares specific, type
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.