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Single cell gene expression profiling of splenic cells in mice treated with gated CD33-CD123 CARs compared to those with conventional CD123 CAR expression

GSE282690 Homo sapiens; Mus musculus Expression profiling by high throughput sequencing 5 samples Submitted 2024/11/29 Platform GPL25431
Summary
Single-cell profiling of specific cells in humanized mice treated with gated and conventional CAR-T cells, illustrating the mechanisms of Cytokine Release Syndrome (CRS) and cross-talk between human and mouse cells in animals presenting with CAR-induced CRS symptoms.
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Direct links to NCBI, no account and no request form: the whole study as GSE282690_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 5 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1189802 and SRA study SRP547154. Searching any of these in the dataset finder brings you back here.

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