GEO series
microRNA-497-5p-based Screening Identifies a Novel Synthetic Lethal-type Interaction via PKMYT1 and WEE1 in Pleural Mesothelioma
GSE282870
Homo sapiens
Expression profiling by high throughput sequencing; Other
24 samples
2026/06/29
GPL20301
Summary
We discovered direct targets of miR-497-5p through biotinylated miRNA pull-down of target mRNA molecules from a epithelial subtype derived diffuse pleural mesothelioma (DPM) cell line (H2052). The pulldowns were done side by side with RNA-seq to capture the effects of miRNA on the transcriptomes of the DPM cells.
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Paper (PMID 40673159) ↗
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