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Comparison of IL10-eGFP+ cells with IL10-eGFP- CD4+ T cells induced by in vivo immunisation

GSE283286 Mus musculus Expression profiling by high throughput sequencing 4 samples Submitted 2024/12/09 Platform GPL19057
Summary
Here we perform QuantSeq 3' mRNA sequencing of RNA extracted from flow sorted splenic CD4+ Il10-eGFP+ or CD4+Il10eGFP- T cells from Tg4 Nr4a3-Tocky Il10-eGFP mice 24 hours after immunisation with 4 mg/kg of [4Y]-MBP. Our aim was to confirm the Tr1 cell phenotype within the Il10-eGFP+ T cell subset
Published in
Interferon-γ and IL-27 positively regulate type 1 regulatory T cell development during adaptive tolerance
Lecky DAJ, Sheriff L, Rouvray ST et al. · iScience 2025 · PMID 40276760 · doi:10.1016/j.isci.2025.112308
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Also filed as BioProject PRJNA1193044 and SRA study SRP548680. Searching any of these in the dataset finder brings you back here.

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