Xin-Zi-Sheng-Wan Decoction Alleviates Hyperuricemia-Induced Renal Injury by Modulating SPP1-CD44-Mediated Macrophage Infiltration and SRC/FAK/β-Catenin Signaling Pathway
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 4 × Mus,CTL vs 4 × Mus,HUA vs 4 × Mus,XZSWGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE300922_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1282677 and SRA study SRP594909. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 3 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9072206 Mus,CTL1 Mus,CTL
- GSM9072207 Mus,CTL2 Mus,CTL
- GSM9072208 Mus,CTL3 Mus,CTL
- GSM9072209 Mus,CTL4 Mus,CTL
- GSM9072210 Mus,HUA1 Mus,HUA
- GSM9072211 Mus,HUA2 Mus,HUA
- GSM9072212 Mus,HUA3 Mus,HUA
- GSM9072213 Mus,HUA4 Mus,HUA
- GSM9072214 Mus,XZSW1 Mus,XZSW
- GSM9072215 Mus,XZSW2 Mus,XZSW
- GSM9072216 Mus,XZSW3 Mus,XZSW
- GSM9072217 Mus,XZSW4 Mus,XZSW
- GSE269309 Mechanistic basis of gene regulation by SRCAP and H2A.Z (RNA-Seq) 30 samples shares src
- GSE289387 Transcriptome response to FAK1 (PTK2) targeting in a murine Nf2 null schwannoma cell line model 24 samples shares fak
- GSE297902 TBK1 enhances antifungal immunity by forming a SRC-TBK1 positive feedback loop in phagosomes of macrophages 22 samples shares src
- GSE272190 The myeloid SRC family kinase HCK regulates breast cancer growth by activating tumor associated macrophage-led invasion and inhibiting cytotoxic T cell activity 20 samples shares src
- GSE248058 Stroma reprogramming by FAK synergizes with MAPK inhibition and renders PDAC responsive to cytotoxic- and immuno-therapies II 18 samples shares fak
- GSE233650 The exposure of prenatal enriched environment promotes fetal neuronal development via activating AHR-Src pathway 16 samples shares src
- GSE313445 Ovarian Tumor FAK Inhibition Releases Omega-3 Fatty Acids Stimulating GATA6 Peritoneal Macrophage CXCL13 Production Enhancing Immunotherapy 16 samples shares fak
- GSE284675 PTH Counteracts Hippo Signaling via Src-dependent YAP Stabilization to Enhance Bone Marrow Stromal Cell Differentiation 12 samples shares src
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.