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Changes in Muscularis Macrophage Populations in Diabetes

GSE283429 Mus musculus Expression profiling by high throughput sequencing 3 samples Submitted 2026/04/28 Platform GPL21103
Summary
Macrophages in the muscle layers of the stomach (Muscularis Macrophages - MMs) play a crucial role in regulating gastric motility and immune homeostasis by interacting with cells in their shared environment and play a central role in development of diabetic gastroparesis, a diabetic complication. The lack of knowledge of the subtypes of murine MMs that reside in the stomach limits a comprehensive understanding of their function and their involvement in disease development.
Published in
Heterogeneity of Muscularis Macrophages in the Stomach
Cipriani G, Ji S, Liu Y et al. · Gastro hep advances 2026 · PMID 42164829 · doi:10.1016/j.gastha.2026.100937
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Also filed as BioProject PRJNA1193638 and SRA study SRP549107. Searching any of these in the dataset finder brings you back here.

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