← BioTransfer GEO Dataset Finder
GEO series

AKR1B10 dictates c-Myc stability to suppress colorectal cancer metastasis via PP2A nitration

GSE283654 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2025/07/22 Platform GPL23227
Summary
To elucidate the mechanisms underlying AKR1B10 deficiency-enhanced metastasis, we performed transcriptome profiling by RNA-seq to explore the signaling pathways affected by AKR1B10.
Published in
AKR1B10 dictates c-Myc stability to suppress colorectal cancer metastasis via PP2A nitration
Wu X, Huang S, Gao J et al. · Science advances 2025 · PMID 40845116 · doi:10.1126/sciadv.adv6937
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE283654_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1194987 and SRA study SRP549758. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 6 more — browse all 6 samples with per-sample file links →

Similar datasets

Search all human RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.