Multiscale integration of tissue and chromatin context converts cell heterogeneity into stable intestinal patterning
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 22 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 22 samples: 8 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE283662_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1194994 and SRA study SRP549854. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 19 samples.
How we read this: 8 replicated groups read from 22 sample titles; they account for 19 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8669068 Foxa1_Input_rep1 Foxa1_Input
- GSM8669069 Foxa1_Input_rep2 Foxa1_Input
- GSM8669070 Foxa1_Input_rep3 Foxa1_Input
- GSM8669071 Foxa1_Input_rep4 Foxa1_Input
- GSM8669072 Foxa1_ChIP_rep1 Foxa1_ChIP
- GSM8669073 Foxa1_ChIP_rep2 Foxa1_ChIP
- GSM8669074 mSIorg_24h mSIorg_24h
- GSM8669075 mSIorg_36h mSIorg_36h
- GSM8669076 mSIorg_48h mSIorg_48h
- GSM8669077 mSIorg_60h mSIorg_60h
- GSM8669078 mSIorg_72h mSIorg_72h
- GSM8669079 mSIorg_84h mSIorg_84h
- GSM9707907 mSIorg_0h
- GSM9707908 mSIorg_24h mSIorg_24h
- GSM9707909 mSIorg_36h_1 mSIorg_36h
- GSM9707910 mSIorg_36h_2 mSIorg_36h
- GSM9707911 mSIorg_48h mSIorg_48h
- GSM9707912 mSIorg_60h mSIorg_60h
- GSM9707913 mSIorg_72h mSIorg_72h
- GSM9707914 mSIorg_84h mSIorg_84h
- GSM9707915 mSIorg_96h
- GSM9707916 mSIorg_108h
- GSE279796 Setdb1 regulates proper differentiation of adult intestinal stem cells via restraining permissive chromatin structure and transcriptional variability 18 samples shares intestinal, chromatin
- GSE297315 Crotonate-activated histone H3K14 crotonylation enhances intestinal regeneration after injury 41 samples shares intestinal
- GSE301970 Multiome analysis of Kras-mutant intestinal epithelium 10 days post-recombination 20 samples shares intestinal
- GSE318068 eIF4G2-mediated Translation Initiation of Histone Modifiers is Essential for Intestinal Stem Cell Maintenance and Differentiation [Multiome] 16 samples shares intestinal
- GSE318069 eIF4G2-mediated Translation Initiation of Histone Modifiers is Essential for Intestinal Stem Cell Maintenance and Differentiation 145 samples shares intestinal
- GSE247946 Regulation of transcriptional signal integration and memory by inflammation-induced chromosome conformation 132 samples shares integration
- GSE241206 Vascular and perivascular cell profiling reveals the molecular and cellular bases of blood-brain barrier heterogeneity 105 samples shares heterogeneity
- GSE294512 eIF4G2-mediated Translation Initiation of Histone Modifiers is Essential for Intestinal Stem Cell Maintenance and Differentiation [RNA-seq] 92 samples shares intestinal
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.