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Effects of SARS-CoV-2 S protein on endothelial cell thrombosis

GSE283771 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2024/12/15 Platform GPL11154
Summary
The outbreak of Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection, has led to an unparalleled global health crisis. While the majority of COVID-19 patients present with mild respiratory issues, a subset of patients still develop severe symptoms and life-threatening complications. Notably, abnormal coagulation and thrombosis are significant contributors to mortality in severe COVID-19 patients. Therefore, this study stimulated aortic endothelial cells with SARS-Cov-2 S protein and performed transcriptome sequencing analysis.
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Direct links to NCBI, no account and no request form: the whole study as GSE283771_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1195572 and SRA study SRP550051. Searching any of these in the dataset finder brings you back here.

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