LMX1B missense-perturbation of regulatory element footprints disrupt postnatal serotonergic forebrain axon arborization [ChIP-seq]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 2 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 2 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- LMX1B missense-perturbation of regulatory element footprints disrupts serotonergic forebrain axon arborizationProceedings of the National Academy of Sciences of the United States of America · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE283963_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1196413 and SRA study SRP550560. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 2 more — browse all 2 samples with per-sample file links →
- GSE283962 LMX1B missense-perturbation of regulatory element footprints disrupt postnatal serotonergic forebrain axon arborization [ATAC-seq] 8 samples shares lmx1b, missense-perturbation, serotonergic, arborization, regulatory, footprints, postnatal, forebrain
- GSE283961 LMX1B missense-perturbation of regulatory element footprints disrupt postnatal serotonergic forebrain axon arborization 12 samples shares lmx1b, missense-perturbation, serotonergic, arborization, regulatory, footprints, postnatal, forebrain
- GSE288803 Proteasome inhibition alleviates proteinuria in Lmx1b knock-in mice with dysfunctional LIM domains 35 samples shares lmx1b
- GSE284418 AMPK phosphorylates LMX1b to regulate a brainstem neurogenic network important for control of breathing in neonatal mice 15 samples shares lmx1b
- GSE253995 Enteric neuronal GPR41-DHX9 signaling senses microbial metabolites to mediate the crosstalk between serotonergic neurons and intestinal stem cells 18 samples shares serotonergic
- GSE310953 A new mouse mutant with a discrete mutation in Pcdhgc5 reveals that the Protocadherin gC5 isoform is not essential for dendrite arborization in the cerebral cortex 12 samples shares arborization
- GSE278037 A serotonergic mechanism is involved in the procognitive effect of CB1R peripheral inhibition in a mouse model of fragile X syndrome 9 samples shares serotonergic
- GSE253990 Enteric neuronal GPR41-DHX9 signaling senses microbial metabolites to mediate the crosstalk between serotonergic neurons and intestinal stem cells [RNA-seq] 6 samples shares serotonergic
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.