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Pathobiont-triggered induction of epithelial IDO1 drives regional susceptibility to Inflammatory Bowel Disease

GSE284294 Mus musculus Expression profiling by high throughput sequencing 20 samples 2026/02/05 GPL24247
Summary
Chelated proximal colon epithelium from wildtype and Tnf(dARE/+) mice in two murine housing facilities (CONV and SPF-B), where the CONV facility mice are naturally colonized with Chlamydia muridarum. Raw data contains all encapsulated cells, while processed data filtered out empty droplets, poor quality cells, and non-epithelial cells such as epithelia-associated or intraepithelial immune cells.
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NCBI GEO page ↗ Paper (PMID 41701533) ↗ {# Names what the click gives you. "Open in finder" meant nothing to a visitor who arrived from a search engine and has never seen the tool. #} Find more mouse RNA-seq datasets →
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