cMaf supports Zeb2 expression for primitive hematopoiesis (FL mono RNA-seq)
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 3 × BM vs 3 × KO vs 3 × Mixed vs 3 × WTGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Transcription factor Maf promotes expression of repressor Zeb2 to drive microglia development in primitive hematopoiesisImmunity · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE284309_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1198502 and SRA study SRP551539. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8682159 BM 1 BM
- GSM8682160 BM 2 BM
- GSM8682161 BM 3 BM
- GSM8682162 KO 1 KO
- GSM8682163 KO 2 KO
- GSM8682164 KO 3 KO
- GSM8682165 Mixed 1 Mixed
- GSM8682166 Mixed 2 Mixed
- GSM8682167 Mixed 3 Mixed
- GSM8682168 WT 1 WT
- GSM8682169 WT 2 WT
- GSM8682170 WT 3 WT
- GSE283975 cMaf supports Zeb2 expression for primitive hematopoiesis (TRM RNA-seq) 24 samples shares zeb2, hematopoiesis, primitive, supports, rna-seq, cmaf
- GSE304528 cMaf supports Zeb2 expression for primitive hematopoiesis (CUT&RUN) 5 samples shares zeb2, hematopoiesis, primitive, supports, cmaf
- GSE267188 The primitive endoderm supports lineage plasticity to enable regulative development [scRNA-Seq] 11 samples shares primitive, supports, rna-seq
- GSE276311 Two mutations associated with leukemia that change a single tyrosine residue in the STAT5B SH2 domain have opposite effects on the transcriptional programs controlling hematopoiesis [RNA-seq] 61 samples shares hematopoiesis, rna-seq
- GSE282840 N6-methyladenosine modulate second cell fate decision by enhancing mRNA stability of pivotal transcription factors during primitive endoderm development [EPSC_RNA-seq] 46 samples shares primitive, rna-seq
- GSE248654 TAF1, the largest subunit of TFIID, is dispensable for adult hematopoiesis [RNA-Seq] 36 samples shares hematopoiesis, rna-seq
- GSE327228 RNA Terminal Uridylyl-Transferases Are Druggable Vulnerabilities in AML, but are Dispensable for Normal Hematopoiesis [RNA-seq] 27 samples shares hematopoiesis, rna-seq
- GSE276312 Two mutations associated with leukemia that change a single tyrosine residue in the STAT5B SH2 domain have opposite effects on the transcriptional programs controlling hematopoiesis [scRNA-seq] 23 samples shares hematopoiesis, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.