← BioTransfer GEO Dataset Finder
GEO series

H3K9me2 CUT&Tag analysis to examine the effect of Jmjd1a knockdown in 3T3-L1 pre-adipocyte cells

GSE284471 Mus musculus Genome binding/occupancy profiling by high throughput sequencing 9 samples Submitted 2025/04/29 Platform GPL34328
Summary
Adipocyte differentiation has been shown to require iron, but the underlying mechanism remains unclear. We have previously reported that iron supply through ferritinophagy is associated with demethylation of the repressive histone mark H3K9me2 in the differentiation-associated genes, which is mediated by the histone demethylase JMJD1A. To examine how JMJD1A regulates the gene expression program during adipocyte differentiation, in this study we peformed H3K9me2 CUT&Tag analysis using 3T3-L1 pre-adipocytes with Jmjd1a knockdown.
Published in
Iron-Dependent JMJD1A-Mediated Demethylation of H3K9me2 Regulates Gene Expression During Adipogenesis in a Spatial Genome Organization-Dependent Manner
Masuda S, Komatsu T, Atia S et al. · Genes to cells : devoted to molecular & cellular mechanisms 2025 · PMID 40289791 · doi:10.1111/gtc.70023
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE284471_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 9 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1199336 and SRA study SRP552037. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 9 more — browse all 9 samples with per-sample file links →

Similar datasets

Search all mouse ChIP / ATAC / CUT&Tag datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.