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Effects of CYTOR Knockdown via CRISPRi on K562 cells

GSE285084 Homo sapiens Expression profiling by high throughput sequencing 8 samples Submitted 2024/12/22 Platform GPL11154
Summary
The long noncoding RNA CYTOR has been linked to poor prognosis of cancer, this includes chemo- and radioresistance. Knowing the mechanisms of CYTOR can benefit current cancer therapeuitics. To examine the mechanisms of CYTOR on K562, we performed CRISPRi to knock it down. RNA sequencing were then performed on these knocked down and wild type cells. This is followed by differential gene expression analysis to determine genes and lncRNAs that are differentially regulated when CYTOR is silenced.
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Direct links to NCBI, no account and no request form: the whole study as GSE285084_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 8 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1201158 and SRA study SRP552999. Searching any of these in the dataset finder brings you back here.

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