Microglial reprogramming enhances antitumor immunity and immunotherapy response in melanoma brain metastases

Direct links to NCBI, no account and no request form: the whole study as GSE285670_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1205401 and SRA study SRP554819. Searching any of these in the dataset finder brings you back here.

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• GSE272424 Rejuvenating endogenous antitumor immunity via a chimeric receptor-engineered oncolytic virus targeting tumor-associated macrophages 6 samples
• GSE326452 Bulk RNA-seq of mouse brain following closed head injury: role of IL-1R1 signaling 200 samples
• GSE278990 Single-cell screens identify ADAM12 as a fibroblast checkpoint impeding anti-tumor immunity 73 samples
• GSE261492 Hypertension Promotes Neuroinflammation, Brain Injury and Cognitive Impairment 48 samples
• GSE300288 Single-cell and spatial transcriptomics analysis of tobacco-associated lung adenocarcinoma development, and in response to targeting inflammation alone or in combination with immune checkpoint blockade in precancerous phase [scRNA-seq] 31 samples
• GSE327176 Single-cell transcriptomic profiling unveils tumor-mediated reprogramming of neutrophils and their unique vulnerability that inhibits metastasis 25 samples
• GSE285471 APOE genotype modifies the gene signature of microglial and astrocytic responses to aging 24 samples
• GSE305453 Perturb-seq uncovers pathological obstacles to direct cardiac reprogramming in vivo 15 samples

Search all mouse RNA-seq datasets in GEO →