GEO series
Bulk RNA-seq of mouse brain following closed head injury: role of IL-1R1 signaling
GSE326452
Mus musculus
Expression profiling by high throughput sequencing
200 samples
2026/07/29
GPL34290
Summary
Bulk RNA-seq was performed on brain tissue from mice following closed head injury (CHI) or sham surgery at 9h, 24h, and 72h post-injury. Four genotypes were studied: C57BL/6J wild-type, IL-1R1 global knockout (gKO), IL-1R1 endothelial restore (eRestore), and IL-1R1 neuronal restore (nRestore) to dissect cell-type specific IL-1R1 signaling contributions to the transcriptomic response to traumatic brain injury.
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Paper (PMID 42488755) ↗
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