Barrier formation by primary human airway epithelial cells sets limits to Staphylococcus aureus adhesion, invasion and cytotoxicity
RNA-seq (gene expression) · human · 24 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 24 samples: 24 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE285788_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1206085 and SRA study SRP555107. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 24 sample titles: 24 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8709038 130122-infect-7days
- GSM8709039 130122-control-7days
- GSM8709040 130122-infect-28days
- GSM8709041 130122-control-28days
- GSM8709042 190619-infect-7days
- GSM8709043 190619-control-7days
- GSM8709044 190619-infect-28days
- GSM8709045 190619-control-28days
- GSM8709046 200718-infect-7days
- GSM8709047 200718-control-7days
- GSM8709048 200718-infect-28days
- GSM8709049 200718-control-28days
- GSM8709050 ARMS126-infect-7days
- GSM8709051 ARMS126-control-7days
- GSM8709052 ARMS126-infect-28days
- GSM8709053 ARMS126-control-28days
- GSM8709054 ARMS132-infect-7days
- GSM8709055 ARMS132-control-7days
- GSM8709056 ARMS132-infect-28days
- GSM8709057 ARMS132-control-28days
- GSM8709058 ARMS92-infect-7days
- GSM8709059 ARMS92-control-7days
- GSM8709060 ARMS92-infect-28days
- GSM8709061 ARMS92-control-28days
- GSE317789 Single-cell and spatial profiling reveal cDC2A-CXCL13+ CD8+ T-epithelial cell crosstalk and cytotoxicity through TNFRSF9 in cutaneous and mucosal lichen planus 42 samples shares cytotoxicity, epithelial
- GSE292944 Culture Media Strongly Influences Primary Human Bronchial Epithelial Cells' Transcriptomic Response to Ozone Exposure 24 samples shares epithelial, primary
- GSE235715 Multi-scaled transcriptomics of chronically inflamed nasal epithelium reveals immune-epithelial dynamics and tissue remodeling in nasal polyp formation 60 samples shares epithelial, formation
- GSE231432 HSC-derived exosomal miR-122- 5p inhibits EMT and fibrosis of intrahepatic biliary epithelial cells to alleviate primary biliary cholangitis 24 samples shares epithelial, primary
- GSE272820 Multi-omics datasets for finer-scale dissection of chromatin architecture alterations in radiation induced malignant transformation of bronchial epithelial cells [Micro-C] 12 samples shares epithelial, formation
- GSE292059 Inflammatory Epithelial and Macrophage Pathways Underlie Residual Asthma Exacerbations in Urban Children Treated with Mepolizumab 965 samples shares epithelial
- GSE276544 MVA-based SARS-CoV-2 vaccine candidates encoding different spike protein conformations induce distinct early transcriptional responses which may impact subsequent adaptive immunity 305 samples shares formation
- GSE285217 Digital transformation of herbal medicine: Conversion to biological entity data using Qi related decoction and constituent herbal medicine-induced transcriptome sequencing_third_A549 270 samples shares formation
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.