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Detecting the whole genomic binding of PARP1 in H1975 cells with CUT&Tag assay.

GSE285816 Homo sapiens Genome binding/occupancy profiling by high throughput sequencing 8 samples Submitted 2025/11/17 Platform GPL24676
Summary
To elucidate the mechanism of EGFR-AS1 on PARP1-DNA binding at genome level, we examined PARP1 binding in response to etoposide stimulation through CUT&Tag technique in H1975 cells which overexpressing EGFR-AS1.
Published in
lncRNA EGFR-AS1 promotes DNA damage repair by enhancing PARP1-mediated PARylation
Gao K, Shi R, Xu C et al. · The Journal of cell biology 2026 · PMID 41335120 · doi:10.1083/jcb.202501091
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Also filed as BioProject PRJNA1206139 and SRA study SRP555149. Searching any of these in the dataset finder brings you back here.

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