Research on the occurrence and progression of colorectal cancer.
RNA-seq (gene expression) · mouse · 15 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 15 samples: 5 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- APX3330 reverses the immunosuppressive tumor microenvironment during colorectal carcinogenesisCancer cell international · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE285835_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1206098 and SRA study SRP555112. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 15 samples.
How we read this: 5 replicated groups read from 15 sample titles; they account for 15 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8709921 Control-1 Control
- GSM8709922 Control-2 Control
- GSM8709923 Control-3 Control
- GSM8709924 AOM+Saline-1 AOM+Saline
- GSM8709925 AOM+Saline-2 AOM+Saline
- GSM8709926 AOM+Saline-3 AOM+Saline
- GSM8709927 AOM+E3330-1 AOM+E3330
- GSM8709928 AOM+E3330-2 AOM+E3330
- GSM8709929 AOM+E3330-3 AOM+E3330
- GSM8709930 AOM+Saline cycle1-1 AOM+Saline cycle1
- GSM8709931 AOM+Saline cycle1-2 AOM+Saline cycle1
- GSM8709932 AOM+Saline cycle1-3 AOM+Saline cycle1
- GSM8709933 AOM+Saline cycle2-1 AOM+Saline cycle2
- GSM8709934 AOM+Saline cycle2-2 AOM+Saline cycle2
- GSM8709935 AOM+Saline cycle2-3 AOM+Saline cycle2
- GSE231802 IL-1R signaling drives enteric glia-macrophage interaction in colorectal cancer progression [bulkRNA-Seq] 36 samples shares progression, colorectal
- GSE252358 Acetylcyssteine synergizes PD-1 blockers against colorectal cancer progression by promoting TCF1+PD1+CD8+ T cell differentiation in mice 10 samples shares progression, colorectal
- GSE223323 Enterocyte like differentiation defines metabolic gene signatures of CMS3 colorectal cancers and provides therapeutic vulnerability 148 samples shares colorectal
- GSE228579 Chronic stress disrupts hepatic homeostasis and accelerates liver cancer progression through ADRB2 signaling 66 samples shares progression
- GSE231804 IL-1R signaling drives enteric glia-macrophage interactions in colorectal cancer 39 samples shares colorectal
- GSE263963 The temporal progression of lung immune remodeling during breast cancer metastasis 38 samples shares progression
- GSE225104 RNA-Seq of gut of colorectal cancer mice fed black rice and control diets 38 samples shares colorectal
- GSE286166 Ceramides drive colorectal cancer metastasis through a revival stemness program [BulkRNAseq_CRISPR] 34 samples shares colorectal
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.