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Effects of circAASS overexpression in human HK2 cells

GSE286356 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2026/03/01 Platform GPL24676
Summary
The mechanism underlying circRNA-mediated maintenance of mitochondrial function remains largely unknown. Our study found circAASS was downregulated in renal cortex from mice suffered ischemic reperfusion (IR)-induced acute kidney injury (AKI). Functional study demonstrated that circAASS regulated mitochondrial homeostasis in tubular epithelial cells (TECs). Therefore, to reveal the mechanisms underlying the anti-injury effects of circAASS in TECs. circAASS was overexpressed in hypoxia/reperfusion treated- human immortalized cell line HK2 cells. RNA sequencing was performed and the dysregulated mRNAs were found.
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Also filed as BioProject PRJNA1208969 and SRA study SRP556472. Searching any of these in the dataset finder brings you back here.

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