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single cell RNA-seq analysis of lung cancer cell lines treated with JTE-607

GSE286399 Homo sapiens Expression profiling by high throughput sequencing 4 samples Submitted 2025/01/14 Platform GPL24676
Summary
To assess the impact of CPA inhibition by JTE-607 on intra-cell-line transcriptomic heterogeneity, we profiled two lung cancer cell lines treated with DMSO or JTE-607 by 3' tag-based single-cell RNA-seq with 10x Chromium. For data analysis, we performed transcriptome quantification at the PAS-based transcript level to generate a PAS-by-cell count matrix, and then investigate the effect of JTE-607 treatment on PAS usage pattern and cellular states.
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Also filed as BioProject PRJNA1209070 and SRA study SRP556552. Searching any of these in the dataset finder brings you back here.

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