Bacterial skin infection imprints bone marrow eosinophils to promote allergic skin-lung crosstalk [Quant_seq]
RNA-seq (gene expression) · mouse · 24 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 24 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Eosinophil innate immune memory after bacterial skin infection promotes allergic lung inflammationScience immunology · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE286908_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1210527 and SRA study SRP557238. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 24 more — browse all 24 samples with per-sample file links →
- GSE334547 ACKR2 aids the regulation of bone marrow eosinophils to promote monocyte differentiation and anti-bacterial immunity 26 samples shares eosinophils, bacterial, promote, marrow
- GSE224703 Bulk transcriptomic profiling of eosinophils from skin and bone marrow during atopic dermatitis 16 samples shares eosinophils, marrow
- GSE326801 Astrocyte-microglia crosstalk via CSF1 and IFNb promotes central nervous system repair 14 samples shares crosstalk, promote
- GSE259429 Antibiotic use during influenza infection augments lung eosinophils that impair lung immunity against secondary bacterial pneumonia 12 samples shares eosinophils, bacterial
- GSE294902 SLC29A3 supports phagosomal antibacterial signaling, and promotes autophagy by activating TRPML1 in mouse dendritic cells 12 samples shares bacterial, promote
- GSE327253 IL15 — Driven Crosstalk Between Liver Sinusoidal Endothelial Cells and CD8⁺ Tissue-Resident Memory T Cells Promotes Inflammation in Alcohol-Associated Hepatitis 12 samples shares crosstalk, promote
- GSE319015 mtDNA leakage promotes neuron-glia crosstalk to induce epilepsy by cGAS-STING-driven neuroinflammation and serine metabolic reprogramming 10 samples shares crosstalk, promote
- GSE331176 Phagosome-mediated activation of STING by purine and pyrimidine-based bacterial cyclic dinucleotides 380 samples shares bacterial
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.