MafB is a conserved transcriptional regulator of macrophage development and identity across tissues and species
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 57 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 57 samples: 19 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- MafB is a conserved transcriptional regulator of macrophage development and functional identity across tissues and speciesImmunity · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE287347_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1212168 and SRA study SRP557234. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 38 samples.
How we read this: 19 replicated groups read from 57 sample titles; they account for 38 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8733427 Macrophage, Mafb KO Female, rep1 Macrophage, Mafb KO Fem…
- GSM8733428 Macrophage, Mafb KO Female, rep2 Macrophage, Mafb KO Fem…
- GSM8733429 Macrophage, Mafb KO Male, rep1 Macrophage, Mafb KO Mal…
- GSM8733430 Macrophage, Mafb KO Male, rep2 Macrophage, Mafb KO Mal…
- GSM8733431 Macrophage, Mafb WT Female, rep1 Macrophage, Mafb WT Fem…
- GSM8733432 Macrophage, Mafb WT Female, rep2 Macrophage, Mafb WT Fem…
- GSM8733433 Macrophage, Mafb WT Male, rep1 Macrophage, Mafb WT Mal…
- GSM8733434 Macrophage, Mafb WT Male, rep2 Macrophage, Mafb WT Mal…
- GSM8746331 Macro Mafb WT, rep1, H3K27 antibody
- GSM8746332 Macro Mafb WT, rep1, IgG control
- GSM8746333 Macro Mafb WT, rep2, H3K27 antibody
- GSM8746334 Macro Mafb WT, rep2, IgG control
- GSM8746335 Macro Mafb KO, rep1, H3K27 antibody
- GSM8746336 Macro Mafb KO, rep1, IgG control
- GSM8746337 Macro Mafb KO, rep2, H3K27 antibody
- GSM8746338 Macro Mafb KO, rep2, IgG control
- GSM8749690 Peritoneum - Liver macrophage, Mafb KO, Multiplexing capture
- GSM8749691 Peritoneum - Liver - Spleen macrophage, Mafb KO, cDNA
- GSM8749692 Peritoneum - Liver macrophage, Mafb WT, Multiplexing capture
- GSM8749693 Peritoneum - Liver macrophage, Mafb WT, cDNA
- GSM8749694 Brain - Colon macrophage, Mafb WT, cDNA
- GSM8749695 Brain - Colon macrophage, Mafb WT, Multiplexing capture
- GSM8749696 Brain - Colon - macrophage , Mafb KO, cDNA
- GSM8749697 Brain - Colon macrophage, Mafb KO, Multiplexing capture, 1
- GSM9267457 BMDM, IgG
- GSM9267458 BMDM WT, MafB1, Rep1 BMDM WT, MafB1,
- GSM9267459 BMDM WT, MafB1, Rep2 BMDM WT, MafB1,
- GSM9267460 BMDM WT, MafB2, Rep1 BMDM WT, MafB2,
- GSM9267461 BMDM WT, MafB2, Rep2 BMDM WT, MafB2,
- GSM9267462 BMDM WT, MafB3, Rep1 BMDM WT, MafB3,
- GSM9267463 BMDM WT, MafB3, Rep2 BMDM WT, MafB3,
- GSM9267464 BMDM KO, MafB1, Rep1 BMDM KO, MafB1,
- GSM9267465 BMDM KO, MafB1, Rep2 BMDM KO, MafB1,
- GSM9267466 BMDM KO, MafB2, Rep1 BMDM KO, MafB2,
- GSM9267467 BMDM KO, MafB2, Rep2 BMDM KO, MafB2,
- GSM9267468 BMDM KO, MafB3, Rep1 BMDM KO, MafB3,
- GSM9267469 BMDM KO, MafB3, Rep2 BMDM KO, MafB3,
- GSM9267470 LPM IgG
- GSM9267471 LPM WT, MafB1, Rep1 LPM WT, MafB1,
- GSM9267472 LPM WT, MafB1, Rep2 LPM WT, MafB1,
+ 17 more — browse all 57 samples with per-sample file links →
- GSE253165 Scalable ultra-high-throughput single-cell chromatin and RNA sequencing reveals gene regulatory dynamics linking macrophage polarization to autoimmune disease. 4 samples shares macrophage, regulator
- GSE3165 Identification of conserved gene expression features across human and murine mammary tumors 354 samples shares conserved, across
- GSE307006 Interferon-γ mediated species-specific immune responses in macrophages to Mycobacterium tuberculosis 37 samples shares macrophage, species
- GSE314446 Human GPR15 deficiency reveals CD8+ T regulatory cell-macrophage crosstalk in intestinal inflammation 16 samples shares macrophage, regulator
- GSE253164 Scalable ultra-high-throughput single-cell chromatin and RNA sequencing reveals gene regulatory dynamics linking macrophage polarization to autoimmune disease [NIH-3T3_K562_ATAC_with_blocking] 1 samples shares macrophage, regulator
- GSE253162 Scalable ultra-high-throughput single-cell chromatin and RNA sequencing reveals gene regulatory dynamics linking macrophage polarization to autoimmune disease [NIH-3T3_K562_ATAC_without_blocking] 1 samples shares macrophage, regulator
- GSE253163 Scalable ultra-high-throughput single-cell chromatin and RNA sequencing reveals gene regulatory dynamics linking macrophage polarization to autoimmune disease [NIH-3T3_K562_RNA_with_blocking] 1 samples shares macrophage, regulator
- GSE243107 O-GlcNAcylation controls pro-fibrotic transcriptional regulatory signaling in hepatic stellate cells 43 samples shares regulator
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.