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Gene expression profiling of WT and Aldh1a1 KO mouse lung tissues exposed to naphthalene

GSE287365 Mus musculus Expression profiling by high throughput sequencing 4 samples Submitted 2025/05/06 Platform GPL24247
Summary
To explore potential impact of Aldh1a1 deficiency in the retinoic acid signaling in the lung, gene expression levels were compared between wildtype and Aldh1a1 deficient lung tissues. The expression levels of retinoic acid responsive genes were very similar between wildtype and Aldh1a1 deficient lungs, suggesting that Aldh1a1 deficiency has minimal impact on retinoic acid signaling.
Published in
Aldehyde metabolism governs resilience of mucociliary clearance to air pollution exposure
Shinjyo N, Kimura H, Yoshihara T et al. · The Journal of clinical investigation 2025 · PMID 40408364 · doi:10.1172/JCI191276
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Also filed as BioProject PRJNA1212218 and SRA study SRP558156. Searching any of these in the dataset finder brings you back here.

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