Discovery, delineation and therapeutic targeting of a hyper-translation pathway driving cytokine release syndrome [BCAP_KO_BMDM_Ribo-seq]

Direct links to NCBI, no account and no request form: the whole study as GSE287440_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 8 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1212761 and SRA study SRP558374. Searching any of these in the dataset finder brings you back here.

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• GSE327213 Increased mRNA translation delays tumor initiation and exposes a therapeutic vulnerability in lung cancer 16 samples
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• GSE334890 Discovery of Tcf7 regulators with clonally-resolved CRISPR screens identifies Trim28 as a mediator of CD8 T cell differentiation in tumors 48 samples
• GSE297441 Development of CAR T cells Targeting U5 snRNP200 for the Treatment of Acute Myeloid and B-Lymphoid Leukemias 19 samples
• GSE331062 Hepatic translation rewiring in insulin deficiency identifies Reg3α as an insulin-independent glucoregulatory factor 16 samples
• GSE303166 A novel CAF population coordinates hyper-suppressive regulatory T cell recruitment and localization in lung cancer 10 samples
• GSE215963 Subclonal evolution revealed by single-cell profiles of expressed mutations identifies adaptation mechanisms to immunotherapy in melanoma. 1497 samples

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